心脏移植后受者抑郁焦虑状况的调查

The depression and anxiety state of heart transplantation patients

目的调查心脏移植受者术后的抑郁焦虑状况。方法共有58例心脏移植受者被纳入研究，由精神科医生采用汉密尔顿抑郁量表（HAMD）和汉密尔顿焦虑量表（HAMA）对受者进行评估。抑郁症和焦虑症的诊断不仅要符合中国精神障碍分类与诊断标准（第三版）（CCMD-3）的诊断标准，并且HAMD得分或HAMA得分需≥14分。支持抑郁症和焦虑症的共病诊断。结果所有受者抑郁症患病率为15．5％（9／58），焦虑症患病率为22．5％（13／58），同时诊断为抑郁症和焦虑症的患病率为13．8％（8／58）。术后1年内受者的抑郁症和焦虑症患病率分别为16．7％（2／12）和33．3％（4／12）。多因素回归分析结果显示，HAMA总分与HAMD总分呈正相关（P〈0．01，95％可信区间为0．6050．834），与其他因素均无明显相关性（P〉0．05）。结论心脏移植受者抑郁症和焦虑症的患病率高，且抑郁和焦虑常合并存在。

Objective To investigate the depression and anxmty state oi heart transplantation patients. Methods Fifty-weight heart transplantation outpatients were assessed by Hamilton Depression Rating Scale （HAMD） and Hamilton Anxiety Rating Scale （HAMA） in Zhongshan Hospital during October 2010 to April 2011. Those diagnosed with depression disorder should meet the criteria of depression in Chinese Classification of Mental Disorder-3nd version （CCMD-3） and the score of HAMD≥14, and those diagnosed with anxiety disorder should meet the criteria of anxiety disorder CCMD-3 and the score of HAMAn14. The diagnoses of concurrent depression and anxiety were made. Results The prevalence of depression disorder and anxiety disorder was respectively 15.5% （9/58） and 22. 5% （13/58）. The prevalence of depression disorder and anxiety disorder within 12 months was respectively 16. 7% （2/12） and 33.3% （4/12）. The score of HAMD was positively related to HAMA score （P〈0.01 ）. Conclusion The prevalence of depression disorder and anxiety disorder is very high and the co-existence of depression and anxiety is very common.