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噬菌体展示技术 被引量:1

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摘要 噬菌体展示技术是将外源蛋白或多肽与噬菌体的一种衣壳蛋白融合表达,融合蛋白则表达在病毒颗粒的表面,而编码这个融合子的DNA则位于该病毒粒子内。噬菌体展示技术使大量随机多肽与其DNA编码序列之间建立了直接联系,可以通过检测病毒内部的DNA,使得各种靶分子的多肽配体通过淘选的体外选择程序而快速鉴定。其在生物医学的诸多领域有着广泛的运用。
出处 《川北医学院学报》 CAS 2011年第6期550-553,共4页 Journal of North Sichuan Medical College
基金 国家自然科学基金项目(30872850) 四川省科技支撑计划项目(2008sz0186)
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  • 8冯俊,李丽,杨洪斌,刘世喜.用噬菌体展示技术筛选喉癌细胞靶向肽的研究[J].华西医学,2011,26(12):1844-1847. 被引量:1

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