高强度聚焦超声在肝癌临床治疗中的应用现状及发展

Clinical application and development of high intensity focused ultrasound in hepatic carcinoma therapy

高强度聚焦超声是一种肝癌局部治疗新技术。与手术治疗和其他局部治疗（如射频消融、肝动脉栓塞化疗、酒精注射等）方法相比，因其具有无创伤、精确度高、肿瘤组织坏死确切及术后并发症少等诸多优势，故得到临床广泛认可。作为一种重要的肝癌治疗手段，该法正逐步普及于临床。本文对高强度聚焦超声治疗肝癌的机制、现状进行综述，并对其临床应用前景和发展方向加以探讨。

High intensity focused ultrasound （HIFU） is a new technology of focal therapy for patients with hepatic carcinoma. Comparing with operation and other focal therapeutic methods （such as radiofrecluency and transeatheter arterial chemoembolization） of liver cancer, HIFU is non-invasive, accurate, and definite in killing the tumor tissue with fewer complications. Thus, it is widely accepted in clinical settings and has a promising prospect. In this article, we review the mechanism and present situation of hepatic carcinoma therapy with HIFU and dicuss some clinical application and development in the future.