摘要
由高盐环境中生长的微生物里分离出的嗜盐酶在高盐度下仍然具有催化活性,工业上具有良好的应用前景。一些嗜盐酶已被克隆纯化出来,它们的分子结构特点也已经被广泛研究。该文从嗜盐酶的蛋白质序列和结构特征等方面综述了嗜盐酶嗜盐的分子结构基础研究进展,分析了存在的问题并对未来工作提出了展望。研究嗜盐酶盐适应性的分子基础,可以为新的功能蛋白的发展和鉴定提供依据。
Halophilic enzymes are isolated from microorganisms lived in the environment with high salt concentration, and this kind of enzyme only functions under high salt conditions. Halophilic enzymes have beenconsidered to have a variety of industrial applications due to their tolerance on salt. Some halophilic enzymes have been cloned and purified and their molecular structural properties have been widely studied. In the present review,the recent progresses of molecular structural basis of halophilic enzymes related to halophilic characteristics are presented. Some questions and the prospects of future studies are also discussed. This review will contribute to afurther understanding of the molecular basis of haloadaptation in halophilic enzymes and will be helpful for devel- oping and identifying functional novel proteins.
出处
《中国细胞生物学学报》
CAS
CSCD
北大核心
2012年第1期91-97,共7页
Chinese Journal of Cell Biology
基金
中国博士后基金(No.20100471579)资助项目~~
关键词
嗜盐酶
盐适应性
分子结构基础
halophilic enzymes
haloadaptation
molecular structural basis