阿托伐他汀钙序贯治疗急性冠脉综合征120例疗效分析

Efficacy analysis of sequential therapy of atorvastatin calcium in 120 cases with acute coronary syndrome

目的 探讨阿托伐他汀钙片序贯治疗对急性冠脉综合征的疗效。方法 选取2010年6月～2011年6月在笔者所在医院治疗的急性冠脉综合征患者240例,随机分为观察组和对照组,两组均给予阿托伐他汀钙片进行治疗,对照组采用常规疗法,观察组采用序贯疗法,比较预后情况、血脂和血清hs-CRP、MMP-3、AngⅡ、PCⅢ改善水平。结果 观察组患者预后明显优于对照组,血脂和血清hs-CRP、MMP-3、AngⅡ、PCⅢ改善水平明显优于对照组,差异有统计学意义(P<0.05)。结论 阿托伐他汀钙片序贯疗法可明显提高急性冠脉综合征患者的治疗效果,改善预后。

Objective To investigate the sequential atorvastatin calcium effect of therapy on patients with acute coronary syndrome.Methods From June 2010 to June 2011 in our hospital,240 cases with acute coronary syndrome were randomly divided into the observation group and the control group.Both groups were given atorvastatin calcium for treatment,control group with conventional therapy,observation group were treated with sequential therapy,compared complications and death,blood and serum hs-CRP,MMP-3,Ang Ⅱ,PC Ⅲ level of improvement.Results The patients prognosis is significantly better than the control group,blood lipids and serum hs-CRP,MMP-3,Ang Ⅱ,PC Ⅲ level of improvement than the control group,significant difference（P 〈 0.05）.Conclusion Atorvastatin calcium sequential therapy can significantly improve the curative effect and the prognosis of acute coronary syndrome.