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帕瑞昔布钠超前镇痛在椎体后凸成形术中的应用 被引量：9

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摘要 经皮穿刺椎体后凸成形术（PKP）是治疗椎体骨质疏松性压缩骨折的较佳选择,该手术创伤小,恢复快,止痛效果明显.但该手术常在局麻下进行,加之患者多数系老年患者,痛阈较低,术中常因患者疼痛不配合致手术中断.帕瑞昔布钠（商品名：特耐）是一种新型高选择性环氧化酶-2（COX-2）抑制剂,其能够有效缓解疼痛,减少胃肠道反应和抗血小板作用,同时其在骨科手术超前镇痛的应用也被许多学者所认可.我院自2009年12月至2011年6月对行PKP手术患者采用两种不同模式镇痛方案,取得了较好的镇痛效果,现报告如下.
作者 吴娟萍 潘国标 王卫 洪菊芹 杨宝根
机构地区 杭州市第一人民医院吴山院区 杭州市肿瘤医院骨科
出处 《中国药物与临床》 CAS 2012年第1期130-131,共2页 Chinese Remedies & Clinics
关键词 椎体后凸成形术 超前镇痛 帕瑞昔布 应用 骨质疏松性压缩骨折 老年患者 手术创伤 抗血小板作用
分类号 R614 [医药卫生—麻醉学]
  • 相关文献

参考文献9

  • 1Burton AW,Reddy SK,Shah HN,et al.Percutaneous vertebro-plasty-a technique to treat refractory spinal pain in the setting of advanced metastatic cancer:a case series.J Pain Symp tom Manage,2005,30:87-95.
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二级参考文献5

  • 1Pogatzki-Zahn E M, Zahn P K. From preemptive to preventive analgesia [J]. Curr Opin in Anaesthesiol, 2006,19.. 551-555.
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共引文献4

同被引文献84

  • 1陈怀龙,王明山,王世端.针刺麻醉的临床应用及前景展望[J].国际麻醉学与复苏杂志,2006,27(6):347-350. 被引量：44
  • 2Demho G, Park SB, Kharasch ED. Central nervous system con- centrations of cycloxygenase-2 inhibitors in human. Anesthesi- ology, 2005,102 (S) : 409-415.
  • 3Ardoin SP, Sundy JS. Update on nonsteri- odal anti - inflammatory drugs. Curt Opin Rheumatol, 2006, 18(3) :221 -226.
  • 4Kanis JA, Burlet N, Cooper C, et al. Eu- ropean guidance for the diagnosis and management of osteoporosis in postmeno- pausal women. Osteoporos Int, 2008, 19 (4) :399 -428.
  • 5Horie J, Murata S, Inoue Y, et al. A stud- y of the influence of the pulmonary function on the angles of thoracic kyphosis and lum- bar lordosis in community - dwelling elder- ly women. J Phys Ther Sci, 2009, 21(2) : 169 - 172.
  • 6DePalma MJ, Ketchum JM, Frankel BM, et al. Percutaneous vertebroplasty for os- teoporotic vertebral compression fractures in the nonagenarians: A prospective study evaluating pain reduction and new symp- tomatic fracture rate. Spine, 2011, 36 (4) :277 -282.
  • 7Nieuwenhuijse M J, van Erkel AR, Dijk- stra PD. Percutaneous vertebroplasty in very severe osteoporotic vertebral com- pression fractures: feasible and benefi- cial. J Vasc Interv Radiol, 2011, 22 (7) :1017 - 1023.
  • 8Rad AE, Kallmes DF. Correlation between preoperative pain duration and percutane- ous vertebroplasty outcome. Am J Neurora- diol, 2011, 32(10) : 1842 - 1845.
  • 9Li X, Yang H, Tang T, et al. Compari- son of kyphoplasty and vertebroplasty for treatment of painful osteoporotic vertebral compression fractures: twelve - month follow- up in a prospective nonrandom- ized comparative study. J Spinal Disord Tech, 2012, 25(3):142- 149.
  • 10Viscusi ER, Gimbel JS, Halder AM, et al. A multiple- day regimen of parecox- ib sodium 20 mg twice daily provides pain relief after total hip arthroplasty. Anesth Analg, 2008, 107 ( 2 ) : 652 - 660.

引证文献9

二级引证文献24

中国药物与临床
2012年 第1期

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