脂筏标记蛋白flotillin-2生理功能的研究进展

Advances in study on physiological functions of marker protein of lipid raft flotillin-2

为了给进一步研究flotillin-2与某些神经退行性疾病(如海绵状脑病等)的关系提供参考,对脂筏标记蛋白flotillin-2的结构及其主要的生理功能进行了综述,提出,进一步研究flotillin-2与某些神经组织退化疾病及肿瘤的关系,对疯牛疯、克雅病、阿尔兹罕默氏病以及肿瘤病的发病机制及治疗研究具有重要意义。

This article reviews the structure and major physiological functions of flotillin-2 confirmed as a marker protein of lipid raft in order to provide references for studying the relationship between flotillin-2 and some neurodegenerative diseases（i, e. spongiform encephalopathy,etc. ）. It was pointed out that it was important for further studying of the relationship of flotillin-2 with neurodegenerative diseases and tumor,which was of great important studying on pathogenesis and treatment approaches of bovine spongiform encephalopathy,Creutzfeld-Jakob disease, Alzheimer ＇ s disease and tumor.