A型肉毒毒素胸大肌注射对缓解假体隆乳术后疼痛的疗效观察

Effect about reducing pain after subpectoral breast aufmentation by injecting Botulinum toxim type A into pectoralis major muscle

目的:观察胸大肌注射A型肉毒毒素(BTXA)对于缓解胸大肌下假体隆乳术后疼痛的疗效。方法:对于2010年12月至2011年4月83例病例进行随机分成两组,注射组43例,在隆乳术中行双侧胸大肌下半部分多点注射A型肉毒毒素,总计100U;对照组40例,术中注射等量生理盐水,后完成手术。应用数字评分法(NRS)对两组术后疼痛情况进行评分统计例数,进行统计学分析。结果:注射组较对照组疼痛发生率,疼痛程度及疼痛时间均有明显下降,P<0.05,具有统计学意义。结论:术中应用A型肉毒毒素注射胸大肌,对于隆乳术后疼痛缓解,安全、有效。

Objective To investigate the clinical effect of pain of patients after breast augmentation by injecting Botulinum toxin type A. Methods The 83 cases in our department from December 2010 to April 2011 were studied. Two groups were randomly divided： therapy group （43 cases） and control group （40 cases）. The patients in therapy group were given intramuscular injection of BTXA into pectoralis major muscle in the operation,the dose is 100U,and those in control group were only given the same dose of 0.9% sodium chloride solution,Every patient pain after operation was evaluated by using Numerical Rating Scales （NRS） and the scores of every grate patient were recorded. Results The number of the pain patients and the pain level in control group were obviously higher than them in therapy group （P 〈0.05）. Conclusion The injection of BTXA into pectoralis major muscle can relieve the pain after breast augmentation, it＇s a safe and effective method.