国产OMOM胶囊内镜诊断不明原因腹痛159例临床分析

Diagnostic value of OMOM capsule endoscopy in 159 patients with unexplained abdominal pain

目的了解国产OMOM胶囊内镜在不明原因腹痛中的诊断价值。方法 2005年10月至2011年9月,应用OMOM胶囊内镜对159例慢性腹痛患者(腹痛组)和268例无任何症状的查体者(查体组)进行检查,对诊断结果进行相关统计学分析。结果慢性腹痛组患者小肠黏膜病变的诊断阳性率为63.1%(99/157),明显高于健康查体人群的18.7%(50/268),两者比较有统计学意义(P<0.05);腹痛组99例小肠黏膜病变中以小肠黏膜非特异性炎症为最多,占39例(24.8%);其次为小肠血管畸形9例(5.7%);小肠肿瘤9例(5.7%);小肠淋巴组织增生8例(5.1%);小肠息肉6例(3.8%);小肠钩虫病6例(3.8%);小肠溃疡5例(3.2%);克罗恩病5例(3.2%);肠结核4例(2.5%);小肠蛔虫病3例(1.9%);小肠黄色瘤3例(1.9%);小肠脂肪瘤2例(1.3%);小肠未发现任何异常58例(36.9%)。结论国产OMOM胶囊内镜在不明原因腹痛的病因诊断中有良好的价值,临床安全性好。

Objective To evaluate the diagnostic value of OMOM capsule endoscopy in patients with unexplained abdominal pain.Methods From Oct 2005 to Sep 2011,OMOM capsule endoscopy was used in 159 patients with chronic abdominal pain（abdominal pain group） and 268 healthy examinees without any symptoms（healthy people group）.The diagnoses by OMOM capsule endoscopy were recorded and compared statistically.Results For small intestinal mucosa lesions in the abdominal pain group,the diagnostic positive rate was 63.1%（99/157）,which was significantly higher than that in the healthy people group（18.7%,50/268）（P0.05）.The 99 patients with small intestinal mucosa lesions in the abdominal pain group included 39 patients suffered from non-specific inflammation of small intestinal mucosa（24.8%）,9 patients with small intestinal vascular malformation（5.7%）,9 patients with small intestinal tumor（5.7%）,8 patients with small intestinal lymphoid hyperplasia（5.1%）,6 patients with small intestinal polyp（3.8%）,6 patients with ancylostomiasis（3.8%）,5 patients with small intestinal ulcer（3.2%）,5 cases of Crohn disease（3.2%）,4 patients with small intestinal tuberculosis（2.5%）,3 patients with ascarid（1.9%）,3 patients with small intestinal xanthoma（1.9%） and 2 patients with small intestinal lipoma（1.3%）.About 36.9%（58/157） patients in the abdominal pain group showed no small intestine abnormity.Conclusion OMOM capsule endoscopy is a safe procedure and a valuable tool in etiological diagnosis of unexplained abdominal pain.