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急性髓系白血病干细胞表型的研究进展

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摘要 迄今大部分急性髓系白血病患者都无法治愈,5年总体生存率仅为20%~30%,大部分患者是由于疾病复发所致。目前认为化疗仅能杀伤白血病原始细胞,而对白血病干细胞无效。因此这可能是白血病复发的根源。不断有新的白血病干细胞(LSCs)表型被确定,从而将LSC同正常造血干细胞区分开来,并研发出针对LSC表型的单克隆抗体。现就近几年LSCs表型的研究进展进行综述。
出处 《国际输血及血液学杂志》 CAS 2012年第1期37-40,共4页 International Journal of Blood Transfusion and Hematology
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