免疫性血小板减少性紫癜中医证候分析

TCM syndromes of immunologic thrombocytopenic purpura

目的观察分析免疫性血小板减少性紫癜中医基本证候。方法回顾性总结149例原发性血小板减少性紫癜(ITP)患者及49例继发性血小板减少症患者住院病例资料,对其临床证候进行统计分析。结果免疫性血小板减少性紫癜发病女性多于男性,证候出现频率高的前3位依次是气虚85.4%,血瘀44.4%,血虚42.4%。结论气虚、血瘀、血虚是免疫性血小板减少性紫癜的主要证候。其出血机制为气不摄血、瘀血内阻致血不循经。

Objective To analyse the basic TCM syndromes of immunologic thrombocytopenic purpura （ITP）. Methods The hospitalization materials were retrospectively summarized in 149 patients with ITP and 49 ones with secondary thrombocytopenia, and the clinical symptoms and syndromes were analysed statistically. Results The cases of ITP onset were more in female patients than in male ones. The first three syndromes with higher occurrence frequency were, in proper order, qi deficiency （85.4%）, blood stasis （44.4%） and blood deficiency （42.4%）. Conclusion The main TCM syndromes of ITP include qi deficiency, blood stasis and blood deficiency. The bleeding mechanism of ITP is related to blood failing to circulate in the vessels induced by qi failing to control blood and internal stagnation of blood stasis.