新型布尼亚病毒感染11例临床分析

Clinical Analysis of 11 Cases With a New Variety of Bunyavirus Infection

目的:探讨新型布尼亚病毒感染的临床特点、治疗及预后。方法:对11例新型布尼亚病毒感染患者生活环境、临床表现、治疗及预后进行回顾性分析。结果:11例患者均急性起病,居住山区,呈散发患者,多发病于夏秋季节。临床表现均有发热、纳差、肌肉酸痛及不同程度的出血,部分患者伴有消化系统及神经、精神症状。经抗病毒、支持、对症治疗9例痊愈,2例死亡。结论:新型布尼亚病毒感染易致发热伴血小板减少,中老年好发,应积极给予支持、对症治疗。

Objective： To investigate the clinical features,treatment and prognosis of a new variety of bunyavirus infection. Methods： Living environment,clinical manifestations,treatment and prognosis of 11 cases with a new variety of bunyavirus infection were analyzed retrospectively. Results： Eleven cases were with acute onset,lived in mountain area, sporadic cases and frequently occurring in summer and autumn. Clinical manifestations were characterized by fever,anorexia,muscle soreness and bleeding in various degree,some cases accompanied with digestive,neurologic and psychiatric symptoms. Nine cases were cured and 2 cases died after antiviral,supportive and symptomatic treatments. Conclusions： A new variety of bunyavirus infection can cause fever with thrombocytopenia. Middle and old aged people are more susceptible to the infection,it should be energetically treated with supportive and symptomatic treatment.