重症监护室革兰阴性杆菌的分布和耐药分析

Distribution and drug resistance analysis of Gram-negative bacteria in ICU

目的:了解我院重症监护室(ICU)2006年-2010年革兰阴性菌的分布和耐药情况。方法:细菌由VITEK全自动鉴定仪鉴定,采用纸片扩散法(K-B法)进行药敏试验。结果:1639株革兰阴性菌中,前4位分别为A.baumanii占26.1%,P.aeruginosa占16.2%,K.pneumomiae占15.0%,E.coli占11.3%,产ESBLs的K.pneumomiae和E.coli的检出率分别为36.2%和62.9%。结论:ICU患者以呼吸道多重耐药非发酵菌感染为主。

Objective：To investigate the distribution and drug resistance of Gram-negative bacteria in the department of ICU in our hospital for improving the management and proper clinical utilization.Methods： The bacteria isolates were identified by VITEK automatic analyzer,Kirby-Bauer method was used for drug sensitivity test.Results： In 1639 strains of Gram negative bacteria,the above four bacteria were A.baumanii（26.1%）,P.aeruginosa（16.2%）,K.pneumomiae（15.0%） and E.coli（11.3%）.The detection rate of K.pneumomiae and E coli producing ESBLs were 36.2% and 62.9% respectively.Conclusion： Among the ICU patients,the majority were respiratory tract infection caused by multi-resistance nonfermenters.