期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

非小细胞肺癌微转移的检测及临床意义进展研究 被引量：2

下载PDF
导出
摘要 肿瘤微转移是引起肿瘤复发和转移的主要原因,也是分子诊断分期的重要依据。肺癌微转移的研究范围包括淋巴结微转移、骨髓微转移、外周血微转移及胸膜腔微转移。检测非小细胞肺癌微转移,对非小细胞肺癌患者的准确分期、治疗方案的选择、手术方案的确定、化疗效果的及时评估和预后预测都起着非常重要的作用。
作者 李建英 刘安 张惠民 郑策
机构地区 西安交通大学医学院附属西安市中心医院呼吸科
出处 《齐齐哈尔医学院学报》 2011年第22期3685-3687,共3页 Journal of Qiqihar Medical University
基金 陕西科技厅科技攻关项目(2007K09-01-(1))
关键词 微转移 非小细胞肺癌 分子学诊断 临床意义
分类号 R734.2 [医药卫生—肿瘤]
  • 相关文献

参考文献20

  • 1Park JW, Kwon TK,Kim IH, et al. A new strategy for the diagnosis of MAGE-expressing caneels[J]. Immunol Methods, 2002,266(1-2).
  • 2D'Cuaba J, Corths BA, Herndon JE, et al. Molecular stang of poly-mersse chain reaction estimation of lymph node mierometastatie tumorcell burden in stage I non- small cell lung cancer: preliminary resultsof Cancerand Leukemia Group9761.
  • 3Ito M, Minamiya Y, Kawai H, et al. Intraoperative detection of lymphnode rnicrometastasis with flow cvtometry in non-small cell lung cancer [J]. Thorac Cardiovasc Surg, 2005, 130 (3) : 753-758.
  • 4Mitas M, Hoover L, Silvestri G, et al. Lunx is a superior molecularmarker for detection of nonsmall cell lung cancer in peripheral blood[J]. Mol Diagn, 2003,5 (4) : 237 - 242.
  • 5Mitas M, Cole DJ, Hoover L, et al. Real-time reveiCOtranscription-PCR detects KS1/4mRNA in mediastinal lymph nodes from patients withnon-small cell lung cancer[J]. Clin Chem,2003,49(2) :312-315.
  • 6Wallace MB,Block MI,Gillanders W,et al. Accurate molecular detection of non-small cell lung cancer metastases in mediastinal lymphnodes sampled by endoscopic ultrasoundguided needle aspiration[J]. Chest, 2005,127(2) : 430-437.
  • 7Dobashi K,Sugio K,Qsaki T,et al. Micremetastatie P53-posirive eellsin the lymph nodes of non-small-cell lung cancer: prognostic significancel[J]. Thorac Cardlovasc Surg, 1997,114 (3) :339-346.
  • 8Ahrendt SA, Yang SC, Wu L, et al. Molecular assessment of lymphnndes in patients with resected stage I non-small cell lung cancer:Pre-liminary resets of a prospective study[J]. Thorac Cardiovasc Surg, 2002,123 (3) : 466 -474.
  • 9Wallace MB, Block M, Hoffman BJ, et al, Detection of telomerase expression in mediastin Mlymph nodes of patients witll lung cancer[J]. Am J Respir Crit Care Med, 2003,167 (5) 1 670-1 675.
  • 10Ohta Y,Oda M,Wu J,et al. Can tumor size be a guide for limited sur-gical intervention in patients with peripheranonan cell lung can-Assessment from the point of view of nodal micrometastasis[J]. Thorac Cardiovasc SurR, 2001,122 ( 5 ) : 900 - 906.

二级参考文献11

  • 1Gu CD, Osaki T, Oyama T, et al. Detection of micrometastatic tumor cells in pNO lymph nodes of patients with completely resected nonsmall cell lung camcer: impact on recurrence and survival [J]. Ann Surg, 2002. 235(1): 133 - 139.
  • 2Wu J. Ohta Y, Minato H, et al. Nodal occult metastasis in patients with peripheral lung adenocarcinoma of 2.0 cm or less in diameter[J]. Ann Thorac Surg, 2001.71(6):1772- 1778.
  • 3Maruyama R, Sugio K, Mitsudomi T, et al. Relationship between early recurrence and micrometastasis in the lymph nodes of patients with stage Ⅰ non-small-cell lung cancer [J]. J Thorac Cardiovac Surg, 1997, 114 (4):535 -543.
  • 4Osaki T, Oyama T. Gu CD. et al. Prognostic impact of micrometastatic tumor cells in the lymph nodes and bone marrow of patients with completely rcsected stage Ⅰ non-small-cell lung cancer [ J ]. J Clin Oncol, 2002, 20 (13) : 2930 - 2936.
  • 5Hashimoto T, Kobayashi Y, Ishikawa Y, et al. Prognostic value of genetically diagnosed lymph node micrometastasis in non-small-cell lung carcinoma cases [J] . Cancer Res, 2000, 60(22): 6472 -6478.
  • 6Kawano R, Heta E, Ikeda S, et al. Micrometastasis to lymph nodes in stage I left lung cancer patients [J]. Ann Thorac Surg, 2002,73(3): 1558 - 1562.
  • 7Ohta Y, Nozawa H, Tanaka y, et al. Increased vascular endothelial growth factor and vascular endothelial growth factor-C and decreased nm23 expression associated with microdissemination in the lymph nodes in stage Inon-small-cell lung cancer [J] . J Thorac Cardiovac Surg, 2000, 119(4): 804 -813.
  • 8刘关键,王家良,康德英,洪旗.四格表数据Meta分析的简明统计方法[J].华西医科大学学报,2000,31(2):265-268. 被引量：62
  • 9孙福红,魏水易,许自明,孙晓红.随机对照试验Meta分析的质量评价[J].药物流行病学杂志,2002,11(1):31-36. 被引量：33
  • 10王洲,殷洪年,张林,蓝心刚,李厚文.肺癌淋巴结隐匿性转移的基因诊断及预后研究[J].中华肿瘤杂志,2002,24(3):247-249. 被引量：18

共引文献12

同被引文献32

  • 1张俊旺,丁悌.Ⅰ期非小细胞肺癌淋巴结微转移的研究进展[J].肿瘤研究与临床,2004,16(5):355-358. 被引量：5
  • 2孙玉鹗.胸外科手术学[M].第2版.北京:人民军医出版社,2004.492-493.
  • 3Hung J J, Jeng WJ, Hsu WH, et al. Predictors, Of death, Local recurrence, And distant metastasis in completely re- sectedpathological stage - I non - small - cell lung cancer [J]. Thorac Oncol,2012; ,7(7) :1115-1123.
  • 4Jiang W, Chen X, Xi J, et al. Selective mediastinal lymph-adenectomy without intraoperative frozen section examinations for clinical stage I non- small- cell lung cancer: retrospective study of 403 cases [ J ]. orld Jsurg, 2013 ;37(2) :392-397.
  • 5Coello MC, Luketich JD, Litle VR, et al. Prognostic significance of micrometastasis in non- small- cell lung ancer[ J]. Clin Lung Cancer,2004 ;5(4) :214-215.
  • 6Kwiatkowski D J, Harpole DH, Strauss GM, et al. Molecular and pathologic markers in stage I non- small- cell zarcinoma of the lung [ J ]. J Clin Oncol, 1995 ; 13 ( 5 ) : [265-1279.
  • 7Allard WJ, Matera J, Miller MC, et al. Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases[J]. Clin Cancer Res ,2004 ;10(20) :6897-6904.
  • 8Chen JT, Cheng YW, Chou MC, et al. The correlation between aberrant connexin 43 mrna expression induced by promoter methylation and nodal small cell lung cancer [ J ]. Clin Cancer Res, 2003 ; 15 ; 9 ( 11 ) :4200-4204.
  • 9Moriya Y, Iyoda A, Kasai Y, et al. Prediction of lymph node metastasis by gene expression profiling in patients with primary resected lung cancer [ J ]. Lung Cancer, 2009;64( 1 ) :86-91.
  • 10Yao H, Zhang Z,Xiao Z, et al. Identification of metastasis associated proteins in human lung squamous carcinoma using two-dimensional difference gel electrophoresis and laser capture microdissection [ J ]. Lung Cancer, 2009 ; 65 ( 1 ) :41-48.

引证文献2

二级引证文献1

齐齐哈尔医学院学报
2011年 第22期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部