高剂量辐照鸡胸肉安全性毒理学评价

SAFETY AND TOXICOLOGY ASSESSMENT OF CHICKEN BREAST FOR HIGH-DOSE IRRADIATION

以10、15和25kGy剂量辐照处理鸡胸肉,通过动物急性毒性试验、Ames试验、骨髓细胞微核试验、精子畸形试验和30d喂养试验,对其食用安全性进行评价。结果表明,雌、雄小鼠急性经口LD50均大于10g/kg.BW,属实际无毒级;Ames试验、小鼠骨髓微核试验、精子畸形试验结果均为阴性;大鼠30d喂养试验各项指标均未见异常。高剂量辐照鸡胸肉属安全的宠物食品。

Feeding wholesomeness tests of irradiated chicken breast were studied by using acute oral toxicology,Ames,micronucleus of born marrow cell,spenm shape abnormality in mice and 30d feeding test.The LD50 of all the rats and mice were more than 10g/kg·BW,which means that the pet foods belonged to actually non-toxic grade;ames test,and the tests of micronucleus of born marrow cell,spenm shape abnormality in mice were all negative results;30d feeding test in rats demonstrated that it had no distinctive effects on routine blood,body weight and biochemical index.It is concluded that pet foods irradiated up to 25 kGy high dose were no safety and toxicology problems.