淮南市2010年手足口病病原检测结果分析

Analysis on Etiological Identification of Hand-foot-mouth Disease in Huainan City

目的了解淮南市手足口病的流行趋势及病原型别鉴定分析。方法对2010年4～12月123例临床诊断手足口病例进行三间分布分析,采用逆转录-聚合酶链反应(RT-PCR)鉴定肠道病毒病原体型别。结果来自哨点医院123例患者中,中心城区(57例)与其他县区之和(66例)发病人数比例约为1:1.16;手足口病以5月为发病高峰,高发年龄集中在1～5岁年龄组,男性患者(85)与女性患者(38)比例约为1:0.45;123份咽拭子标本病原鉴定阳性数95例,阳性率77.2%(EV71:CA16约为2:1)。结论淮南市手足口病的流行在地域分布无明显的地域差别,有明显的流行季节及年龄分布,患者以EV71感染为主,同时伴有CA16及其他型别肠道病毒感染。

Objective To study the epidemic feature and etiological identification of the hand-foot-and-mouth Disease in Huainan city.Methods To analyze region,season and age distributions of 123 hand-foot-and-mouth cases diagnosed by clinicians in Huainan city during the period from April to December,2010.The pathogen of enteocvirns was identified by reverse transcriptase PCR（RT-PCR）.Results Of 123 cases,57 cases occurred in City and 66 cases occurred in the other counties.The incidence peak occurred from April to August.Most cases were children at age of 1-5.Ratio of male cases（85） and female cases（38） was 2.24：1.95 viruses were isolated from 123 throat swab specimens.The positive rate was 77.2%（EV71： CA16 was about 2：1.）.Conclusion No obvious geographical distribution differences of HFMD were observed in Huainan.But there were obvious epidemiological features of season and groups patients.EV71 was a main pathogen.