期刊文献+

全身炎症反应综合征患者血清D-二聚体、乳酸在预后评估中的价值 被引量:1

下载PDF
导出
摘要 目的评价D-二聚体、乳酸在全身炎症反应综合征患者预后中的价值。方法 120例SIRS患者按照诊断标准的项目数,分为A1组、A2组、A3组;根据是否由感染诱发分为B1组(sepsis组)、B2组(非sepsis组);根据疾病结局分为MODS组和非MODS组,死亡组和存活组,比较各组的血D-二聚体、乳酸水平。结果 SIRS组D-二聚体、乳酸水平、均高于非SIRS组(P<0.01),各亚组间A3组、A2组间D-二聚体、乳酸水平均高于A1组(P<0.01和P<0.05);B1组(sepsis组)D-二聚体、乳酸水平高于B2组(非sepsis组)(P<0.01);MODS组、死亡组D-二聚体、乳酸水平高于非MODS组和存活组(P<0.05和P<0.01)。结论 SIRS时血浆D-二聚体、乳酸水平明显升高,并与病情危重程度有密切关系,测定D-二聚体、乳酸对判断SIRS患者炎症反应程度和预后有重要意义。
机构地区 浙江省中医院
出处 《浙江实用医学》 2011年第6期403-404,407,共3页 Zhejiang Practical Medicine
  • 相关文献

参考文献11

二级参考文献18

  • 1胡森,盛志勇,周宝桐.创伤后多器官衰竭发病过程的“双相预激”学说[J].解放军医学杂志,1995,20(5):361-361. 被引量:30
  • 2Houard X,Rouzet F,Touat Z,et al.Topology of the fibrinolytic system within the mural thrombus of human abdominal aortic aneurysms[J].J Pathol,2007,212(1):20-28.
  • 3Courtney DM,Steinberg JM,McCormick JC.et al.Prospective diagnostic accuracy assessment of the HemosIL HS D-dimer to exclude pulmonary embolism in emergency department patients[J].Thromb Res,2010,125(1):79-83.
  • 4Tokita Y,Kusama Y,Kodani E,et al.Utility of rapid D-dimer measurement for screening of acute cardiovascular disease in the emergency setting[J].J Cardiol,2009,53(3):334-340.
  • 5Suzuki T,Distante A,Zizza A,et al.Diagnosis of acute aortic dissection by D-dimer:the International Registry of Acute Aortic Dissection Substudy on Biomarkers (IRAD-Bio) experience[J].Circulation,2009,119(20):2702-2707.
  • 6Eggebrecht H,Naber CK,Bruch C,et al.Value of plasma fibrin D-dimers for detection of acute aortic dissection[J].J Am Coll Cardiol,2004,44(4):804-809.
  • 7Shitrit D,Bar-Gil Shitrit A,Rudensky,J.et al.Determinants of ELISA D-dimer sensitivity for unstable angina pectoris as defined by coronary catheterization[J].Am J Hematol,2004,76(2):121-125.
  • 8Shitrit D,Bar-Gil Shitrit A,Rudensky B,et al.Role of ELISA D-dimer test in patients with unstable angina pectoris presenting at the emergency department with a normal electrocardiogram[J].Am J Hematol,2004,77(2):147-150.
  • 9Frost SD,Brotman DJ,Michota FA.Rational use of D-dimer measurement to exclude acute venous thromboembolic disease[J].Mayo Clin Proc,2003,78(11):1385-1391.
  • 10Fuster V,Badimon L,Badimon JJ,et al.The pathogenesis of coronary artery disease and the acute coronary syndromes[J].N Engl J Med,1992,326(5):310-318.

共引文献1473

同被引文献14

  • 1何志捷,陈纯,蒋龙元,施旖旎.MODS患者血清多种细胞因子、C反应蛋白和D-二聚体水平的意义以及与预后的关系[J].中国病理生理杂志,2004,20(11):2114-2117. 被引量:6
  • 2高伟,王增智,刘双,肖利.APACHE Ⅱ,SOFA评分和血小板计数对高龄MODS患者预后的研究[J].北京医学,2007,29(8):479-480. 被引量:8
  • 3Barie YS,Hydo LJ ,Fischer E,et al. Development ot multi-pie organ dysfunction syndrome in critically ill patients with perforated viscus. Predictive value of APACHE sever- ity scoring[J]. Arch Surg, 1996,131 (1) :37-43.
  • 4Barie PS, Hydo LJ. Epidemiology of multiple organ dys- function syndrome in critical surgical illness[J]. Surg In- fect, 2000,1 (3) : 173-185.
  • 5Kim H J, Son YK, An WS. Effect of sodium bicarbonate administration on mortality in patients with lactic acido- sis:a retrospective analysis [J]. PLoS 0ne,2013,8(6): e65283.
  • 6Permpikul C, Noppakaorattanamanee K,Tongyoo S,et al. Dynamics of central venous oxygen saturation and serum lactate during septic shock resuscitation[J]. J Med Assoc Thai (English), 2013,96 (Suppl 2 ) : $232-237.
  • 7Uzoigwe CE, Venkatesan M, Smith R, et al. Serum lactate is a prognostic indicator in patients with hip fracture [J]. Hip Int, 2012,22(5) : 580-584.
  • 8De Raes EA,Benoit DD,Depuydt PO,et al. Early recog- nition of malignant lactic acidosis in clinical practice:re- port on 6 patients with haematological malignancies [J]. Acta Clin Belg, 2012,67 (5) : 347-351.
  • 9Yanagida Y,Gando S,Sawamura A,et al. Normal pro- thrombinase activity,increased systemic thrombin activi- ty, and lower antithrombin levels in patients with dissem- inated intravascular coagulation at an early phase of trau- ma:Comparison with acute coagulopathy of trauma-shock [J]. Surgery,2013,154(1):48-57.
  • 10黄斌,王导新,程远.APACHE Ⅱ评分系统在SICU中MODS患者病情评估的应用[J].重庆医学,2010,39(10):1193-1195. 被引量:21

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部