摘要
[目的]使用Meta分析方法分析年龄与乳腺癌患者保乳术后局部复发的关系。[方法]检索关于年龄与乳腺癌保乳术后具有复发关系的文献,采用Meta分析。[结果]共有5篇文献符合纳入标准,乳腺癌保乳术后患者5188例,其中"年轻"患者380例,"年老"患者4808例。Meta分析显示相对于"年老"患者,"年轻"患者术后局部复发风险增加(OR=3.73,95%CI:1.64～8.49)。以40岁为界限,≤40岁组术后局部复发风险增加(OR=4.10,95%CI:1.55～10.85)。[结论]"年轻"乳腺癌患者保乳术后局部复发风险增高,≤40岁患者局部复发明显高于>40岁患者。
[Purpose] To evaluate the relationship between age and local recurrence in patients with breast cancer after conserving surgery by meta analysis.[Methods] The literature concerning the association between age and local recurrence was searched.A Meta analysis was performed.[Results] Five articles,including 5 188 patients were involved in this study.Of them there were 380 younger patients and 4 808 elder patients.Meta analysis showed that compared to elder patients,the risk of local recurrence in younger patients was significantly increased（OR=3.73,95%CI：1.64～8.49）.Forty years old as a cut-off age,the risk of local recurrence in ≤40 year old patients was significantly increased（OR=4.10,95%CI：1.55～10.85）.[Conclusion] The risk of local recurrence in younger breast cancer patients after conserving surgery is higher than those in 40 years old patients.
出处
《肿瘤学杂志》
CAS
2011年第12期923-927,共5页
Journal of Chinese Oncology
关键词
年龄
乳腺肿瘤
复发
保乳手术
META分析
age
breast neoplasms
local recurrence
breast conserving treatment
meta analysis
