摘要
目的:观察尼莫地平与氟桂利嗪治疗偏头痛的临床效果。方法:随机将190例偏头痛患者分为两组,观察组96例,给予尼莫地平30 mg/次,每日3次,对照组92例给予氟桂利嗪5 mg/次,每晚1次。结果:尼莫地平与氟桂利嗪治疗偏头痛的临床疗效差异无统计学意义(P>0.05),但不良反应差异有统计学意义(P<0.05)。结论:尼莫地平与氟桂利嗪治疗偏头痛的临床疗效相当,但尼莫地平不良反应较氟桂利嗪少,是目前较为理想的防治偏头痛的药物。
Objective:To explore the clinical efficacy of nimodipine and flunarizine in treatment of migraine.Methods:190 patients with the diagnosis of migraine were randomly divided into experimental group(n=96) and control group(n=92).It was treated for nimodipine(30 mg,three times daily) in experimental group.The control group was treated with flunarizine(5 mg,nightly).Results:There was no significant difference between two groups in efficacy(P0.05).But significant difference was found in side-effect(P0.05).Conclusions:Nimodipine showed the same effect in treatment of migraine with flunarizine and had less side-effects than flunarizine.Nimodipine was thought to be an ideal drug for migraine.
出处
《南通大学学报(医学版)》
2011年第6期448-449,共2页
Journal of Nantong University(Medical sciences)
基金
苏州科技计划项目(SYS201122)