川穹嗪联合倍他乐克对慢性心力衰竭的疗效观察

Objective To Observe Chuan Qiong Hydrochloride Combined with Metoprolol in the Treatment of Chronic Heart Failure

目的:观察川穹嗪联合倍他乐克对慢性心力衰竭的治疗效果,指导临床用药。方法:68例慢性心力衰竭患者随机分为两组(对照组和治疗组),对照组给予倍他乐克治疗,治疗组采用川穹嗪和倍他乐克联合治疗。结果:治疗组的总有效率高于对照组(P<0.05),治疗组患者心功能改善情况优于对照组(P<0.05),治疗组患者血清炎症因子ICAM-1、TNF-α和CRP的水平明显低于对照组(P<0.05)。治疗期间,患者未发生严重不良反应。结论:川穹嗪和倍他乐克具有协同作用,两者联合治疗慢性心力衰竭疗效显著,安全可靠。

Objective：To observe Chuan Qiong hydroehloride combined with metoprolol in the treatment of chronic heart failure. Methods： 68 patients with chronic heart failure were randomly divided into two groups （control and treatment groups）, the control group was given metoprolol treatment, the treatment group were treated with hydrochloride combined with metoprolol. Results ： The total effective rate of control group was higher than trealment group（P 〈 0.05）, improvement in cardiac function of treatment group was better than the control group（P 〈 0.05）, serum inflammatory factors ICAM -- 1, TNF - α and CRP levels of treatment group were significantly lower than the control group（P 〈 0 05） . During treatment, patients with no serious adverse reactions. Conclusion： Chuan Qiong hydrochloride and metoprolol had synergistic effect, combination of the two in the treatment of chronic heart failure effect is significant, safe and reliable.