期刊文献+

GM-CSF增强免疫调节作用的研究进展 被引量:1

原文传递
导出
摘要 DNA疫苗免疫哺乳动物存在免疫原性差和免疫效果不理想的诸多问题,因而影响DNA疫苗的免疫效果和应用性。如果要获得效力更持久、反应强度更优化的免疫应答,需要进一步改善DNA疫苗的免疫效果。根据目前的研究,
出处 《疾病预防控制通报》 2011年第6期76-78,共3页 Bulletin of Disease Control & Prevention(China)
基金 国家自然科学基金项目资助(30760136) 自治区动物学重点学科资助(20101102)
  • 相关文献

参考文献18

  • 1郭成,刘青光,杨威,姚英民.融合基因GM-CSF/IL-2转基因瘤苗在肝癌特异性免疫治疗中的应用[J].南方医科大学学报,2008,28(2):188-192. 被引量:5
  • 2张文卿,于修平.基因佐剂在DNA疫苗中的应用[J].国外医学(免疫学分册),2004,27(6):350-353. 被引量:2
  • 3T. Jones,A. Stern,R. Lin.Potential role of granulocyte-macrophage colony-stimulating factor as vaccine adjuvant[J]. European Journal of Clinical Microbiology & Infectious Diseases . 1994 (2)
  • 4SondereggerI,IezziG,MaierR,etal.GM-CSF mediates au-toimmunitybyenhancingIL-6-dependentTh17 cell develop-ment and survival. The Journal of Experimental Medicine . 2008
  • 5Melkebeek V,Verdonck F,Stuyven E,et al.Plasmid-en-coded GM-CSF induces priming of the F4 (K88)-specificserum IgA response by FaeG DNA vaccination in pig. Vaccine . 2006
  • 6Zaharoff DA,Rogers CJ,Hance KW,et al.Chitosan solu-tion enhances the immunoadjuvant properties of GM-CSF. Vaccine . 2007
  • 7Qing YI,Chen M,Zhao JJ,et al.Construction of an HBVDNA vaccine by fusion of the GM-CSF gene to theHBV-S gene and examination of its immune effects in nor-mal and HBV-transgenic mice. Vaccine . 2010
  • 8Verkade MA,Wetering JVD,Klepper M,et al.Peripheralblood dendritic cells and GM-CSF as an adjuvant for hepati-tis B vaccination in hemodialysis patients. Kidney International . 2004
  • 9Hirata Y,Egea L,Dann SM,et al.GM-CSF-facilitated den-dritic cell recruitment and survival govern the intestinalmucosal response to a mouse enteric bacterial pathogen. Cell Host&Microbe . 2010
  • 10C Hartoonian,M Ebtekar,H Soleimanjahi,A Karami,M Mahdavi,N Rastgoo,K Azadmanesh.Effect of immunological adjuvants: GM-CSF (granulocyte-monocyte colony stimulating factor) and IL-23 (interleukin-23) on immune responses generated against hepatitis C virus core DNA vaccine. Cytokine . 2009

二级参考文献5

共引文献5

同被引文献13

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部