磷钨酸/硅胶催化剂催化合成环己酮乙二醇缩酮

Catalytic Synthesis of Cyclohexanone Ethylene Ketal over Phosphotungstic Acid/silica Gel

以环己酮和乙二醇为原料合成环己酮乙二醇缩酮,考察了磷钨酸/硅胶催化剂对缩酮反应的催化活性。结果表明,磷钨酸/硅胶催化剂是合成环己酮乙二醇缩酮的良好催化剂,确定了最佳合成条件:n(环己酮)∶n(乙二醇)=1∶1.4,磷钨酸/硅胶催化剂用量为反应物总质量的0.2%,带水剂环己烷用量为8 mL,反应时间为30 min。在此条件下,环己酮乙二醇缩酮的收率可达76.4%。

Cyclohexanone ethylene ketal was synthesized with cyelohexanone and glycol as the materials, and the catalytic activity of phosphotungstic acid/silica gel catalyst in ketol reaction was studied. According to the results, silicotungstic acid/silica gel （SG） is a good catalyst for the synthesis of cyclohexanone ethylene ketal. The optimum synthesis conditions were identified： n （cyclohexanone） ： n （glycol） = 1： 1.4, amount of watercarrying agent （i. e. cyclohexane） ： 8 mL, reaction time： 30 min. The yield of cyclohexanone ethylene ketal can reach 76.4% at such conditions.