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血清胱抑素C在急性肾损伤的诊断价值 被引量:4

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摘要 急性肾损伤(acute kidney injury,AKI)临床多见,危害大。其住院患者发病率在国内为0.12%~0.41%病死率为5%~37.9%。国外发病率为2.38%~20%,病死率约为47.8%~56.4%,在重症监护病房(ICU)中病死率高达37%~76.19%。尽管治疗上已经有了重大进步,但AKI的发病率和病死率仍居高不下。基础研究已经明确阐述了AKI的发病机制,但对人类的平行研究结果却令人失望。一个主要的原因是缺乏似心肌梗死中肌钙蛋白一样的早期诊断生物标志物。导致难以早期诊断、早期治疗嶂』。目前在临床上用血肌酐水平来诊断AKI,但其不是反映急性肾功能改变的可靠指标。临床局限性很大。
出处 《中国实用医药》 2011年第35期159-160,共2页 China Practical Medicine
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