期刊文献+

氯吡格雷的临床研究进展 被引量:5

下载PDF
导出
摘要 氯吡格雷作为继阿司匹林后新的一类噻吩吡啶类抗血小板药,能有效降低急性冠脉综合征(ACS)的发病率和死亡率,近年来,随着抗血小板治疗在ACS治疗中的重要性越来越突出,氯吡格雷的临床应用也越来越广泛。本文通过考察国内外一系列的临床案例,探讨氯吡格雷在ACS患者和经皮冠状动脉介入治疗(PCI)术中应用的临床效果和安全性。
作者 孙斌
出处 《中国实用医药》 2011年第35期246-248,共3页 China Practical Medicine
  • 相关文献

参考文献8

二级参考文献45

  • 1韩雅玲,王守力,李毅,荆全民,马颖艳,王祖禄,王冬梅,栾波,王效增.急性冠状动脉综合征患者冠状动脉支架术前高负荷量氯吡格雷预治疗近期疗效[J].中国介入心脏病学杂志,2005,13(1):9-12. 被引量:53
  • 2陈绍良.急性冠状动脉综合征.理论与实践最前沿,2005,5:80-83.
  • 3CAPRIE Steering Committee.A randomized,Blinded,trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)[J].Lancet,1996,348:1329- 1339.
  • 4CURE-Study Investigators.Effects of Clopidogrel in Addition to Aspirin in Patients with Non-ST Elevation.Acute Coronary Syn-dromes[J].N Eng Med.August,2001,345:494-502.
  • 5CURE Study Investigators.Long-term cost-effectiveness of clopidogrel given for up to one year in patients with acute coro-nary syndromes without ST-segment elevation[J].J Am Coll Cardiol,2005,45(6):838-45.
  • 6M¨1ller I,Besta F,Schulz C,et al.Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement[J].Thromb Haemost,2003,89(5):783-787.
  • 7Matetzky S,Shenkman B,Guetta V,et al.Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction[J].Circulation,2004,109(25):3171-3175.
  • 8M¨1ller I,Seyfarth M,Rudiger S,et al.Effect of a high dose of clopidogrel on platelet function in patients undergoing coronary stent placement[J].Heart,2001,85(l):92-93.
  • 9Hermann A,Weber AA,Schror K.Clopidogrel inhibits platelet adhesion and platelet-dependent mitogenesis in vascular smooth muscle cells.Thromb Res,2002,105:173-175.
  • 10Herbert JM,Tissinier A,Defreyn G.Inhibitory effect of clopidogrel on platelet adhesion and intimal proliferation after arterial injury in rabbits.Arterioscler Thromb,1993,13:1171-1179.

共引文献105

同被引文献51

二级引证文献35

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部