脑梗死合并代谢综合征的临床研究

Clinical study of cerebral infarction with metabolic syndrome

目的观察脑梗死合并代谢综合征(MS)的临床特征并探讨MS与脑梗死危险因素的关联性。方法 120例脑梗死患者中65例MS患者列入研究组,55例非MS者列入对照组,收集所有患者临床资料,比较两组患者基本资料、神经功能缺损评分和相关生化指标。结果两组患者在性别和年龄方面差异无统计学意义(P>0.05),但研究组发病率和神经功能缺损评分显著高于对照组,差异均有统计学意义(P<0.05);研究组患者C-反应蛋白、尿酸、纤维蛋白原指标均显著高于对照组(P<0.05),空腹血糖指标极显著高于对照组(P<0.01)。结论 MS临床发病率高、患者神经功能缺损严重,与脑梗死的相关危险因素存在关联性,应加强预防与控制。

Objective To observe the clinical features of cerebral infarction with metabolic syndrome （MS）, and discuss the relationship between MS and risk factors for cerebral infarction. Methods Sixty-five MS cases in 120 cerebral infarction patients were distributed into study group and other 55 cases without MS were distributed into control group. Clinical informations of all the patients were collected and the basic information, neurological deffclt scores and biochemical indicators of two groups were compared. Results Two groups had no significant difference in sex and age （P〉0.05）. Study group had a higher incidence than control group and average patients＇ neurological deficit score in study group was significantly higher than control group （P〈0.05）. The C-reactive protein, uric acid and fibrinogen in study group were significantly higher than those of control group （P〈0.05）, and fasting blood sugar level was more significantly higher than that of con- trol group （P〈0.01）. Conclusion MS had a high incidence and patients with MS had severe neurological deficits. It had re- lationship with risk factors for cerebral infarction and should be strengthened for prevention and control.