地尔硫辅治变异性心绞痛疗效观察

The effect observation of diltiazem in variant angina

目的观察地尔硫辅治变异型心绞痛的疗效。方法将50例变异型心绞痛患者随机分为地尔卓组和对照组各25例。在常规治疗基础上,对照组给予单硝酸异山梨酯泵注,地尔硫组给予地尔卓泵注。治疗后观察2组临床疗效、心绞痛发作次数及持续时间。结果 2组总有效率均为100.0%,差异无统计学意义(P>0.05)。2组治疗后心绞痛发作次数减少,持续时间缩短(P<0.05)。结论地尔硫辅治变异型心绞痛安全、有效。

Objective To investigate the effect of diltiazem in the therapy of variant angina.Methods 50 cases patients with variant angina were randomly divided into diltiazem group and control group,each of 25 cases.On the basis of conventional therapy,control group were treated with lsosorbide mononitrate,diltiazem group were treated with diltiazem.After treatment,compared the clinical effect,pectoris frequency and duration of angina in two groups.Results The total effective rate of two groups all was 100.0%（P0.05）.After treatment,pectoris frequency of angina reduced,duration shortened（P0.05）.Conclusion Diltiazem in the treatment of variant angina is effective and safe.