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高血压合并糖尿病患者动脉硬化指数与微量白蛋白尿的相关性研究 被引量:3

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摘要 目的分析高血压合并2型糖尿病患者动态动脉硬化指数(AASI)与微量白蛋白尿(MAU)的相关性。方法选取高血压合并2型糖尿病患者96例,根据患者是否存在MAU分为研究组对照组各48例。分别进行24h动态血压监测。比较2组AASI、颈动脉内膜厚度(IMT)、MAV、血压及血肌酐等指标,并计算肾小球滤过率(GFR)。结果与对照组相比,研究组AASI、IMT、舒张压、脉压、血低密度脂蛋白(LDL)及血肌酐明显较高(P<0.05),而GFR明显较低(P<0.05)。AASI与MAU、IMT、脉压差及LDL呈正相关(r值和P值分别为r=0.56A,P=0.002;r=0.241,P=0.016;r=0.351,P=0.012;r=0.180,P=0.026),与GFR呈负相关(r=0.118,P=0.021);而多元回归分析显示:AASI仅与MAU呈正相关。结论高血压合并2型糖尿病患者的AASI与MAU呈明显正相关,可联合预测患者的预后及病情变化。
作者 池祥波
出处 《临床合理用药杂志》 2012年第4期112-113,共2页 Chinese Journal of Clinical Rational Drug Use
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