屈罗酮炔雌醇片预防治疗曼月乐放置后阴道出血的临床研究

A Clinical Research on Vagina Bleeding of Prevention Treatment of Drospirenone and Ethinylestradiol Tablets after Inserting Mirena

目的观察口服屈罗酮炔雌醇片3个月预防治疗放置曼月乐后阴道点滴出血的临床效果。方法回顾性分析2009年3月-2010年10月于本院门诊放置曼月乐的患者75例的临床资料,其中放置曼月乐后即口服屈罗酮炔雌醇片3个月者39例和未口服屈罗酮炔雌醇片者36例,于放置曼月乐后第1、2、3个月随访,比较两组出现阴道不规则出血等异常情况及患者使用后的满意率。结果口服屈罗酮炔雌醇片组阴道不规则出血发生率低于未口服屈罗酮炔雌醇片组,两者比较差异具有统计学意(P<0.05);而痛经程度、月经量、比较,两者差异无统计学意义(P>0.05)。放置曼月乐后即口服屈罗酮炔雌醇片患者满意率达97.4%。结论放置曼月乐后即口服屈罗酮炔雌醇片可有效预防治疗阴道点滴出血,值得临床上推广应用。

Objectives to observe clinical effect of vagina spotting bleeding by taking drospirenone and ethinylestradiol tablets for 3 months after inserting mirena.Methods This paper retrospectively analyzes 75 clinical materials of patient inserted mirena at outpatient from March 2009 to October 2010,in which 36 cases immediately taking drospirenone and ethinylestradiol tablets for 3 months after inserting mirena and 36 cases not taking it;following-up in the first,second and third months after inserting mirena,it compares abnormal situations like irregular vagina bleeding and the satisfaction rate after application.Results The incidence rate of taking drospirenone and ethinylestradiol tablets group is lower than the other one,their comparison difference has statistical meaning（P〈0.05）.The satisfaction rate of patients who immediately taking drospirenone and ethinylestradiol tablets after inserting mirena is up to 97.4%.Conclusions Taking immediately drospirenone and ethinylestradiol tablets after inserting mirena can effectively prevent vagina spotting bleeding that is worth to popularization and application in clinical.