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急性冠状动脉综合征的诊断与治疗新进展 被引量：10

Advances in Diagnosis and Treatment of Acute Coronary Syndrome
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摘要 急性冠状动脉综合征导致心血管事件的主要原因是动脉粥样硬化斑块的破裂和血栓形成。不稳定斑块纤维帽较薄,脂质成分多,大量炎性细胞浸润,基质金属蛋白酶含量多。不稳定斑块的临床识别手段有冠状动脉造影、血管内超声、高分辨核磁共振、冠状动脉血管镜、电子束CT及C反应蛋白、CD40L、基质金属蛋白酶、胰岛素样生长因子、白介素(IL)-1、IL-6、IL-8等的测定。急性冠状动脉综合征的治疗有药物治疗与再灌注治疗两大方面,药物治疗包括抗血小板、抗凝、抗缺血、调脂治疗等。再灌注治疗对于无条件进行经皮冠状动脉介入治疗的ST段抬高型心肌梗死患者,在急性心肌梗死3～12 h内溶栓治疗为首选,经皮冠状动脉介入治疗适宜于所有急性冠状动脉综合征患者。目前治疗性血管生成、干细胞移植尚处于试验阶段。 The main causes of cardiovascular events caused by acute coronary syndrome （ ACS ） are atherosclerotic plaque rupture and thrombosis. The unstable plaques have a thinner fibrous cap, plentiful lipid components, infiltrating inflammatory cells, and other distinctive markers. The treatment for ACS is drug treatment and reperfusion therapy. Other possible treatments are therapeutic angiogenesis and stem cell transplantation. This article reviews advancements made in the diagnosis and treatment of ACS.
作者 胡一平 唐惠芳
机构地区 吉首大学医学院
出处 《心血管病学进展》 CAS 2012年第1期131-134,共4页 Advances in Cardiovascular Diseases
关键词 急性冠状动脉综合征 诊断 治疗 新进展 acute coronary syndrome diagnosis treatment advances
分类号 R541.4 [医药卫生—心血管疾病]
  • 相关文献

参考文献20

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二级参考文献35

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心血管病学进展
2012年 第1期

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