依达拉奉联合疏血通治疗老年人急性脑梗死

Clinical observation on edaravone combined with Shuxuetong in treatment of elderly patients with acute cere- bral infarction

目的探讨依达拉奉联合疏血通治疗老年人急性脑梗死的临床疗效。方法120例急性脑梗死患者按照治疗方法的不同分为观察组和对照组各60例，两组均采取常规治疗，对照组采用川穹嗪注射液治疗，观察组采用依达拉奉联合疏血通治疗，比较两组患者的临床疗效、日常生活活动能力（ADL）及神经缺损评分。结果观察组基本痊愈25例，显著进步18例，进步12洌，总有效率为91．7％；对照组总有效率为75．0％，两组差异有统计学意义（X2=6．86，P〈0．05）。观察组的ADL、神经功能缺损评分均显著优于对照组（均P〈0．05）。结论在常规治疗的基础上采用依达拉奉联合疏血通治疗急性脑梗死的可显著促进患者神经功能恢复，值得临床推广。

Objective To explore the chnical effect of edaravone combined with Shuxuetong in treatment of elderly patients with acute cerebral infarction. Methods 120 cases of acute cerebral infarction, according to the dif- ferent treatment methods, were divided into two groups. The conventional treatment was given in two groups, the control group plus Chuanqiong hydrochloride injection, and the observation group adopted edaravone and Shuxuetong. The clinical efficacy, activities of daily living （ADL） and neurological deficit score were compared between two groups. Results There were 25 cases of basic recovery, 18 cases of significant progress, progress in 12 cases in the observa- tion group,total effective rate was 91.7% （55/60） ,the control group was 75.0% （45/60） ,the difference was statisti- cally significant（ X2 = 6.86, P 〈 O. 05 ）. Observation group had statistically significant difference than the control group between ADL and neurological deficit scores （ all P 〈 0.05 ）. Conclusion On the basis of conventional therapy, the use of edaravone combined with Shuxuetong for acute ischemic stroke patients could significantly promote the recovery of neurological function and was worthy of promotion.