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急性脑出血患者血清肿瘤坏死因子-α、白细胞介素-6水平变化 被引量:3

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摘要 目的探讨急性脑出血患者血清肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)水平变化及临床意义。方法采用酶联免疫吸附试验(ELISA)分别检测45例观察组和45例对照组血清TNF-d、IL-6水平;同时检测观察组治疗前后血清TNF—α、IL-6水平。结果观察组血清TNF-α[(13.11±1.93)ng/L]、IL-6[(0.34±0.32)ng/L]水平与对照组[分别为(2.23±1.22)ng/L、(0.04±0.01)ng/L]差异均有统计学意义(t=4.367、3.582,均P〈0.05);观察组患者治疗前后血清TNF-αd、IL-6水平变化差异均有统计学意义(t=4.351、3.826,均P〈0.05)。结论TNF-α、IL-6与脑出血患者发生、发展及预后密切相关,外周血TNF—α、IL-6可作为病情变化的重要指标之一。
作者 邢丽菲
出处 《中国基层医药》 CAS 2012年第1期94-95,共2页 Chinese Journal of Primary Medicine and Pharmacy
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