2010年深圳市福田区人群乙型肝炎的免疫水平

Surveillance of antibody levels of hepatitis B in Futian District of Shenzhen in 2010

目的了解深圳市福田区人群乙型肝炎(乙肝)免疫水平,为制定免疫规划策略提供参考。方法随机抽取辖区内7个年龄组共569名调查对象,采用ELISA双抗原夹心法检测乙肝病毒表面抗体(抗-HBs)。结果 569名调查对象抗-HBs阳性率为74.69%,其中男性74.37%;女性为75.00%;随着年龄增长,人群抗-HBs阳性率逐步下降,差异有统计学意义;免疫次数和抗体阳转率呈正相关。结论目前深圳市福田区适龄儿童的乙肝抗体阳性率较高,应加强成人乙肝免疫预防工作。

[Objective]To understand the antibody levels of hepatitis B in Futian District of Shenzhen City,and provide reference for developing immunization strategy. [Methods]A total of 569 investigation targets were selected randomly from 7 age groups.ELISA double antigen detection was employed to detect hepatitis B virus antibody（anti-HBs）. [Results]The anti-HBs positive rate was 74.69%,among which 74.37% were males and 75.00% were females.With the increasing age,the anti-HBs positive rate in the population decreased gradually,and a statistically significant difference was found.The times of immunization and seroconversion rate were positively correlated. [Conclusion]At present,the anti-HBs positive rate of school-aged children in the Shenzhen Futian district is relatively high.It is necessary to strength the adult immunoprophylaxis against hepatitis B infection.