宫颈上皮内瘤变76例处理探讨

Management strategy with 76 cases of cervical intraepithelial neoplasia

目的探讨宫颈LEEP锥切诊断和治疗宫颈上皮内瘤的临床效果及手术前后病理的变化。方法对76例宫颈上皮内瘤变(CINI.CINⅡ、Ⅲ)患者实行宫颈LEEP锥切术,并对手术治疗前后组织病理诊断差异进行比较。结果 76例患者术后病理65例符合宫颈上皮内瘤变(CINI.CINII.CINIII),3例浸润癌。锥切术后来再治疗的CIN患者中,随访中发现3例再次出现宫颈病变。结论宫颈LEEP术能准确的诊断宫颈病变,并能较好治疗CIN。

Objective To evaluate the clinical effects of loop eleetrosurgieal excision procedure（LEEP） in the diagnosis and treatment of cervical intraepithelial neoplasia（CIN） and analyze pathological changes of the preoperative and postoperative CIN. Methods LEEP was performed in 76 cases with CIN. Analysis was conducted as to the difference in pathologic diagnosis of the cervical mucosa between preoperative and postoperative CIN. Results Pathological analysis identified 65 cases of CIN （ I. II. IlI） , and 3 cases of invasive cervical carcinomas. Follow-up saw recurrence of cervical dysplasia in 3 cases. Conclusion LEEP is ideal and effective in the diagnosis and treatment of CIN and is worth to be recommended in clinic.