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一种治疗母畜子宫内膜炎凝胶剂的研制 被引量:2

Preparation of Gelata Used to Treat the Endometritis in Dam
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摘要 制备一种治疗母畜子宫内膜炎的凝胶剂即复方醋酸氯己定凝胶,并建立其质量标准。方法:以醋酸氯己定和甲硝唑为主药,卡波姆940为基质制备凝胶剂,采用HPLC法测定凝胶剂中醋酸氯己定和甲硝唑含量。结果:该制剂为乳白色或淡黄色半固体凝胶,醋酸氯己定和甲硝唑精密度和重复率良好,平均回收率分别为99.23%和99.37%。该制剂制备工艺简单,含量测定方法准确,重现性好。 The experiment was conducted to prepare Compound Chlorhexidine Acetate Gel,it was used to treat the endometritis in dam, and establish its quality control method. The Compound gelata was prepared with Chlorhexidine Acetate and Metronidazole as chief medicine using carbopol-940 as base. The content of Chlorhexidine Acetate and Metronidazole in the gel was determined by HLPC method. The results showed the preparation was white or light yellow semisolid gel, and had good precision and repetion rate about Chlorhexidine Acetate and Metronidazole.The mean recoveries were 99.23% and 99.37%. The preparation is simple in preparation process,and the determination is accurate and reproducible.
出处 《中国动物保健》 2012年第1期24-27,共4页 China Animal Health
基金 郑州市科技计划课题(10PTGN430)
关键词 复方醋酸氯己定凝胶 制备 质量控制 Compound Chlorhexidine Acetate Gel preparation quality control
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