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乙型肝炎病毒polyA形成与调节因素研究进展

Molecular biological progress in hepatitis B virus 3′end maturation
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摘要 乙型病毒性肝炎(乙肝)是全球范围的重大公共卫生问题之一,其病原体乙型肝炎病毒(HBV)可通过多种途径感染人体,引起急性肝炎、慢性肝炎、肝硬化甚至肝癌。HBV感染是全球十大死因之一,世界上30%的人感染过或者成为HBV的携带者。据统计[1],全球共有3.5亿HBV慢性感染者,每年因HBV慢性感染所致的肝纤维化或者肝癌感染致死的人数有100万左右。
出处 《中国病毒病杂志》 CAS 2011年第6期412-415,共4页 Chinese Journal of Viral Diseases
基金 国家"十一五"艾滋病和病毒性肝炎等重大传染病防治科技重大专项(2008ZX10002-011) 国家重点基础研究发展计划(2007CB512804) 国家国际科技合作与交流专项(2011DFA31030) 德中跨学科重大合作项目(TRR60)
关键词 乙型肝炎病毒 RNA转录 RNA剪切 3′末端形成 Hepatitis B virus RNA transcription RNA splicing 3′end maturation
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参考文献30

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