小儿重症手足口病并发脑炎的MRI表现

MRI manifestations of encephalitis in children with severe hand-foot-mouth disease

目的:探讨小儿重症手足口病(HFMD)并发脑炎的MRI表现。方法:回顾性分析24例小儿手足口病并发脑炎的MRI表现。结果:24例小儿脑部病变共69处病灶。病变多发13例,对称性分布10例,非对称性3例;多发病灶以脑白质病变为主,共37处病变;病变单发11例,其中累及丘脑2例,累及基底节区4例,累及脑干2例,累及颞叶1例,额叶2例。病变主要表现为T1WI上呈稍低或低信号,T2WI、T2-FLAIR及DWI上呈稍高或高信号的斑片、斑点状影,边缘模糊,部分病灶于T2-FLAIR或DWI序列上显示清楚。结论:小儿重症手足口病并发脑炎的MRI表现有一定特征性,对其诊断具有较高敏感度,可观察病变部位、范围和程度,为临床诊治提供参考。

Objective：To investigate the MRI manifestations of encephalitis in children with severe hand-foot-mouth disease（HFMD）.Methods：Imaging materials of 24cases of encephalitis in children with SHFMD were analyzed retrospectively.Results：There were 69lesions in 24cases with children＇s SHFMD.Multiple lesions were presented in 13cases,including 10cases of symmetrical lesions and 3cases of asymmetricay lesions.Multiple lesions mostly involved white matter（n= 37）.11cases manifested single lesions which involved thalamencephalon（n=2）,basal ganglia（n=4）,brain stem （n=2）, lobus temporalis（n=1）,and frontal lobe（n=1）.The lesions were mostly patchy hyporntense/sligtly hypointense on T1WI and hyperintense/slightly hyperintense on T2WI,T2-FLAIR and DWI with blurred border,some lesions were shown clearly on T2-FLAIR or DWI.Conclusion：Characteristice features of encephalitis in children with SHFMD are shown on MRI and have high sensitivity in the diagnosis.MRI can show position,extent and severity in diagnosing encephalitis in children with SHFMD. 【