摘要
目的:探讨磁共振弥散加权成像(DWI)、弥散张量成像(DTI)对Marchiafava-Bignami病(MBD)的诊断及预后评价的价值。方法:对10例MBD患者行DWI检查,其中4例再行DTI检查。结果:本组急性型8例,DWI显示病灶区信号明显增高,并有4例出现弥散受限改变;胼胝体膝部、压部的各向异性分数(FA)值与正常值比较差异有统计学意义(P<0.05),额叶白质、半卵圆中心白质与正常值比较差异也有统计学意义(P<0.05)。结论:MBD的DWI、DTI改变可能反映其临床及预后。
Objective： To investigate the clinicoradiologic characteristics ol Marchlatava-131gnaml disease （MISD） and to charac- terize the value of DWI,DTI and 1 H-MRS in its diagnosis and prognosis. Methods： The clinical and neuroimaging findings of 10 MBD patients were prospectively analyzed. Diffusion-weighted imaging（DWI） were performed in all cases as well as diffusion- tensor imaging in four cases. Results： DWI showed markedly hyper-intensity with diffusion restriction in eight cases in acute phase with ADC values 0. 30~0. 59 ）〈 10-a mm2/s in eight patients manifested as acute onset. The FA values in genus,spleni- um of corpus callosum compared to the control group had statistic difference,as well as in white matter of frontal lobe and cen- tra semiovale. Conclusion： The DWI,DTI features of MBD may be associated with the clinical spectrum and prognosis.
出处
《中国中西医结合影像学杂志》
2011年第6期493-495,I0001,共4页
Chinese Imaging Journal of Integrated Traditional and Western Medicine
