期刊文献+

GM-CSF分泌型肝癌疫苗对荷瘤鼠肿瘤生长及TNF-α的影响

下载PDF
导出
摘要 肝细胞癌(HCC)是世界上常见的恶性肿瘤之一,东亚地区特别是中国是其高发区之一。手术切除和肝移植是目前最有效的治疗方法,但术后复发率较高,而且大部分患者被诊断时已失去手术机会。经肝动脉栓塞化疗、射频消融等治疗方法在临床的广泛应用,延长了患者的生存时间,但5年生存率仍然较低。肝癌对化疗放疗均不敏感,
出处 《肝脏》 2011年第6期483-484,共2页 Chinese Hepatology
基金 南京市医学科技发展项目(200801083)
  • 相关文献

参考文献10

  • 1KULIK LM.Advancements in hepatocellular carcinoma.Cur Opin Gastroentterol,2007,23:268-274.
  • 2Llovet JM,Burroughs A,Bruix J.Hepatocellular carcinoma. Lancet,2003,362:1907-1917.
  • 3Chang DZ,l.omazow W,Joy Somberg C,et al.Granulocytemacrophage colony stimulating factor:an adjuvant for cancer vaccines.Hemotology,2004,9:207-215.
  • 4Dranoff G,Jaffee E,Lazenby A,et al.Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent,specific,and long lasting anti-tumor immunity.Proc Natl Acad Sci USA,1993,90: 3539-3543.
  • 5Aussilhou B,Panis Y,Alves A,et al.Tumor Recurrence After Partial Hepatectomy for Liver Metastases in Rats:Prevention by In Vivo Injection of Irradiated Cancer Cells Expressing GM-CSF and IL-12.J Surg Res,2008,149:184-191.
  • 6Jaffee EM,Thomas MC,Huang AY,et al.Enhanced immune priming with spatial distribution of paracrine cytokine vaccines.J Immunother,2003,19:176-183.
  • 7谢丛华,周云峰.肿瘤坏死因子的多重临床意义[J].国外医学(内科学分册),2005,32(6):247-249. 被引量:12
  • 8Lyu MA.Rosenblum MG.The immunocytokine scFv23/TNF sensitizes HER-2/neu-over expressing SKBR-3 cells to tumor necrosis factor(TNF)via up-regulation of TNF recptor-1.Mol Cancer Ther,2005,4:1205-1213.
  • 9Ohtani T,Nakamura T,Toda K,et al.Cyclophosphamide enhances TNF alpha-induced apoptotic cell death in murine vascular endothelial cell.FEBS Lett,2006,580:1597-1600.
  • 10Gasson JC.Molecular Physiology of Granulocyte-Macrophage Colony- Stimulating Factor.Blood,1991,77:1131-1142.

二级参考文献15

  • 1Carswel IEA, Old L.I, Kassel RL, et al. [J]. Proc Natl Acad Sci U S A, 1975,72:3666-3670.
  • 2Chopra DP,Menard RE,Januszewski J,et al. [J].Cancer Letters ,2004,203 ( 2 ) : 145-154.
  • 3Borst SE. [J]. Endocrine, 2004,23 (2-3) : 177-182.
  • 4Choy EHS. [J]. Drugs Aging, 1998,12 :139.
  • 5Wimett L. [J]. Nurse Pract,2003,28(10):40-48.
  • 6Zheng SX,Vrindts Y,Lopez M,et al. [J]. Maturitas, 1997,26:63-71.
  • 7Nanes MS. [J]. Gene,2003,321:1-15.
  • 8Roggia C, Gao Y, Cencei F, et al. [J]. J Biol Chem,2001,98 : 13960-13965.
  • 9Kimble RB,Bain S,Pacifici R,et al.[J].J Bone Miner Res, 1997,12:935-941.
  • 10An J, Tzagarakis-Foster C, Scharschmidt TC, et al.[J]. J Boil Chem,2001,276:17808-17814.

共引文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部