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血清视黄醇蛋白4与胰岛素抵抗相关的肝脏疾病研究进展

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摘要 一、RBP4的结构和生理功能 血清视黄醇结合蛋白4(RBP4)属于视黄醇结合蛋白(Retinol-Binding Protein,RBP)家族的成员。血清RBP4为分泌型RBP,是一种单一肽链的蛋白质,相对分子质量为21KDa,由181个氨基酸残基组成。1968年RBP4首先在人类的血清中分离出,随后在其他脊椎动物中如鸟类和鱼类也分离出RBP4。按照其序列的同源性可以将RBP分为五类:血清视黄醇结合蛋白、胞内视黄醇结合蛋白、胞内视黄酸结合蛋白、
出处 《肝脏》 2011年第6期500-502,共3页 Chinese Hepatology
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参考文献26

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