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干扰素作用机制及其在抗口蹄疫病毒中的应用研究进展 被引量：7

Interferons and its Applications in Anti-FMDV
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摘要 干扰素(interferon,IFN)是人和动物细胞受到适宜刺激产生的一种微量的、具有高度生物学活性的糖蛋白,是一种具有广谱抗病毒、抗肿瘤、抗多发性硬化、抑制细胞增长和免疫调节作用的细胞因子。自20世纪50年代末发现干扰素以来,相关研究取得了巨大进展。文章综述了干扰素的抗病毒机制及其在抗口蹄疫病毒中的应用进展。 Interferon is a kind of glycoproteins with a high degree of biological activity,synthesized and secreted by somatic cells of all mammalian species when stimulated properly;with the function of broad-spectrum anti-viral,anti-tumor,anti-multiple sclerosis,inhibiting cell growth and mediating immune response.Since the discovery of interferon 50 years ago,great progress has been made so far.This article reviews the signal transduction,anti-virus mechanisms and their application in anti-FMD.
作者 孙静静 邵军军 常惠芸
机构地区 中国农业科学院兰州兽医研究所家畜疫病病原生物学国家重点实验室国家口蹄疫参考实验室甘肃省生物检测工程技术研究中心
出处 《中国畜牧兽医》 CAS 北大核心 2012年第1期206-209,共4页 China Animal Husbandry & Veterinary Medicine
基金 甘肃省重大科技专项(092NKDA030) 转基因专项(2009ZX08006-002B)联合资助
关键词 干扰素 口蹄疫 inteferons FMD
分类号 S852.659.6 [农业科学—基础兽医学]
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中国畜牧兽医
2012年 第1期

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