速眠新和异氟烷对蟒蛇的全麻效果研究

Research on Sumianxin and Isoflurane Anesthesia for Burmese Python

本试验通过使用速眠新和异氟烷两种常用全身麻醉剂对缅甸蟒的麻醉效果进行了研究。对15条蟒蛇肌肉注射和腹腔注射(0.1、0.2、0.4mL/kg)速眠新麻醉剂和对6条蟒蛇使用异氟烷吸入性麻醉后,进行麻醉效果的评估。试验结果表明,常规动物2～4倍的速眠新Ⅱ注射剂对蟒蛇的麻醉效果不明显;4%的异氟烷吸入性麻醉剂可用于蟒蛇的诱导麻醉,2.5%的异氟烷可用于蟒蛇的维持麻醉,其麻醉效果显著,具有诱导麻醉迅速、维持麻醉稳定、肌松作用好、安全性高、可控性强、苏醒快、副作用小等优点。结果显示,异氟烷吸入性麻醉剂可运用于蟒蛇的临床麻醉保定中。

To evaluate the efficacy and safety of general anesthesia with Sumianxin vs isoflurane in Burmese python（Python molurus bivittatus）.15 pythons were anesthetized with Sumianxin-Ⅱ（0.1,0.2,0.4 mL/kg） i.m.and i.p.,6 pythons were anesthetized with isoflurane inhalation.Analgesic effect,righting reflex,breathing,muscle relaxation,time of anesthesia induction,time of recovery from anesthesia,side effects were recorded.High doses of Sumianxin-Ⅱ which is 2-4 times higher than that used in conventional animals did not show good anesthetic efficacy.In contrast,isoflurane when used 4% for anesthesia induction and 2.5% for maintenance showed satisfactory efficacy with notable advantages of induction rapidly,good anesthetic efficacy,muscle relaxation,high safety,recovery quickly and less side effects etc.Isoflurane inhalation anesthesia can be used clinically in pythons safely and effectively.