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不同水平糖耐量个体生长分化因子-15水平及相关性分析 被引量：2

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摘要 生长分化因子-15（growth differentiation factor-15,GDF-15）是转化生长因子-β超家族的成员之一。主要参与调节器官生长、分化及组织修复等多种生物学过程,发挥抗炎症反应、抗细胞凋亡和血管内皮保护等作用。已发现存在糖尿病肾病、胰岛素抵抗的患者血清GDF-15水平均增高,并且认为是1型糖尿病肾病的预后判断因素[1-2]。本研究观察不同糖耐量患者GDF-15水平,观察其与糖耐量受损严重程度的相关性。
作者 刘云涛
机构地区 三峡大学仁和医院内分泌科
出处 《广东医学》 CAS CSCD 北大核心 2012年第2期297-297,共1页 Guangdong Medical Journal
关键词 生长分化因子-15 糖耐量受损 相关性分析 转化生长因子-β超家族 1型糖尿病肾病 水 个体 血管内皮保护
分类号 R541.4 [医药卫生—心血管疾病]
  • 相关文献

参考文献10

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  • 6SCHLITTENHARDT D,SCHOBER A,STRELAU J,et al.Involvementofgrowth differentiation factor-15 /macrophage inhibitory cytokine-1 (GDF-15 /MIC-1) in oxLDL-induced apoptosis of human macrophages in vitro and in arteriosclerotic lesions[J].Cell Tissue Res,2004,318(2):325-333.
  • 7张翼飞,詹维伟,洪洁,顾卫琼,杨义生,桂明辉,唐金凤,王卫庆,刘建民,赵咏桔,宁光.糖耐量受损人群颈动脉内中膜厚度与各代谢指标的关系[J].中华糖尿病杂志（1006-6187）,2005,13(1):23-26. 被引量：35
  • 8王先令,陆菊明,潘长玉,田慧.糖尿病前期尿白蛋白排泄率和微量白蛋白尿患病率的比较[J].中华内科杂志,2004,43(3):170-173. 被引量：42
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二级参考文献28

  • 1田慧,潘长玉,陆菊明,孔祥涛,陆小平,姚晨,蒋赐恩,邓心新,王淑玉,朱艳,崔岚,王正升.糖代谢异常人群中冠心病、高血压的患病率及危险因素调查[J].中华内科杂志,1996,35(5):306-309. 被引量：18
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  • 10Michele MD, Panico S, Celentano E, et al. Association of Impaired glucose homeostasis with preclinical carotid atherosclerosis in women: impact of the new American diabetes association criteria. Metabolism, 2002, 51:52-56.

共引文献326

同被引文献23

引证文献2

二级引证文献9

广东医学
2012年 第2期

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