摘要
益生菌通过促进树突状细胞释放细胞因子，改变Th1／Th2平衡，使免疫反应向Th1细胞方向进行，抑制Th2细胞反应，从而增强宿主的免疫功能。研究表明益生菌在特异性皮炎、哮喘及过敏性鼻炎等IgE相关过敏性疾病的预防和治疗中发挥一定的作用，但由于过敏性疾病的病因复杂、诱因众多，目前益生菌对其作用尚无一致的结论，需进一步进行循证医学研究。
Probiotics stimulate dendritic cells exert regulatory functions by promoting the release of cytokines,which change the balance of Th1/Th2. This process mediates Thl cell response instead of Th2 to enhance immune function. Probiotics have shown preventive and therapeutic potential for diseases, including several IgE-related diseases, such as atopic dermatitis, asthma and allergic rhinitis. However, because of complex causes and numerous incentives, there is no consistent conclusion regarding probiotics application in allergic diseases. Further evidence-based medical researches will be required in the future.
出处
《国际儿科学杂志》
2012年第1期71-74,共4页
International Journal of Pediatrics
