期刊文献+

热熔挤出技术在口服缓控释制剂中的应用进展 被引量:4

下载PDF
导出
摘要 本文对热熔挤出技术的原理、设备、常用物料以及在缓控释制剂中的应用现状等方面进行详细论述,指出目前热熔挤出技术制备口服缓控释制剂存在的问题,并对其发展前景进行展望。
出处 《解放军药学学报》 CAS 2011年第6期544-547,552,共5页 Pharmaceutical Journal of Chinese People's Liberation Army
基金 国家自然科学基金课题面上项目 No.81073064
  • 相关文献

参考文献1

二级参考文献20

  • 1杨睿,唐星,黄惠锋.热熔挤出技术提高水飞蓟素溶出度的初步研究[J].中国新药杂志,2005,14(11):1305-1308. 被引量:25
  • 2SPEISER P.Galenic aspects of drug effects[J].Pharm Acta Helv,1966,41(6):321-342.
  • 3SERAJUDDIN AT.Solid dispelrsion of poorly water-soluble drugs:early promises,subsequent problems,and recent break-throughs[J].J.Phrm Sci,1999,88(10):1058-1066
  • 4VERRECK G,SIX K,MOOTER GV,et al.Characterization of solid dispersions of itraconazole and hydroxypmpylmethylcellulose prepared by melt extrusion-partI[J].Int J Pharm,2003,251(1/2):165-174.
  • 5BAERT LEC,VERRECK G,DANY T.Antifungal compositions with improved bioavailability:US Pat:2003082239[P].2003-05-01.
  • 6CROWLEY MM,SCHROEDER B,FREDERSDORF A,et al.Physicochemical properties and mechanism of drug release from ethyl cellulose matrix tablets prepared by direct compression and hot-melt extrusion[J].Int J Pharm,2004,269(2):509-522.
  • 7YOUNG CR,KOLENG JJ,MCGINITY JW.Production of sphereical pellets by a hot-melt extrusion and sphereonization processs[J].Int J Pharm,2002,242(1/2):87-92.
  • 8LIU J,ZHANG F,MCGINITY JW.Properties of lipophilic matrix tablets containing phenylpropanolamine hydrochloricde prepared by hot-melt extrusion[J].Eur J Pharm Biopharm,2001,52(2):181-190.
  • 9MEHUYS E,VERVAET C,GIELEN I,et al.In vitro and in vivo evaluation of a matrix-in-cylinder system for sustained drug dclivery[J].J Controlled Release,2004,96(2):261-271.
  • 10NAKAMICHI K,YASUURA H,FUKUI H,et al.Evaluation of a floating dosage form of nieerdipine hydrochloricde and hydroxylpropylmethylcellulose acetate suceinate prepared using a twin-screw extruder[J].Int J Pharm,2001,218(1/2):103-112.

共引文献25

同被引文献14

引证文献4

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部