河南省136例<8月龄麻疹病例母亲的抗体水平调查

Measles Antibody Level in the 136 Mothers of Measles Cases under 8 Months in Henan Province

目的了解<8月龄麻疹病例母亲的抗体水平,为mother with Measles制定小月龄婴儿麻疹预防策略提供参考。方法选择河南省136例<8月龄麻疹病例的母亲作为研究组,选择272例非麻疹病例母亲作为对照组,分别采集外周静脉血并分离血清,采用酶联免疫吸附试验检测血清中麻疹免疫球蛋白(Immunoglobulin,Ig)G抗体。结果病例母亲组IgG抗体阳性率为98.53%(134/136),几何平均滴度1:8016.78,高于非麻疹病例母亲组(97.79%,266/272)。结论由于母亲隐性感染、母子同患麻疹等原因,病例母亲组的IgG抗体水平高于非麻疹病例母亲组。在育龄期妇女中开展健康教育是控制婴儿麻疹高发的措施之一。

Objective To know the measles antibody level of measles cases mother, and provide evidence for establishing scientific strategies for measles elimination. Methods 136 measles cases mothers were chosen for case group, and 272 non measles mothers were control groups, blood samples were collected and measles immunoglobulin （Ig） G antibody were detected. Results the positive rate of the case group is 98.53% （134/136）, geometric mean titer is 1： 8016.78, and the IgG antibody level of the case group is higher than control groups （97.79 % ）. Conclusion Because of inapparent infection or mother and the infant infected measles virus simultaneously or successively, the antibody level of the case mother group is higher than the control groups. It is one of strategies for measles control among infants to conduct health education to the reproductive women.