期刊文献+

巴曲酶、低分子肝素、小剂量阿司匹林联合治疗短暂性脑缺血发作的疗效 被引量:5

原文传递
导出
摘要 目的探讨巴曲酶、低分子肝素、小剂量阿司匹林联合应用治疗短暂性脑缺血发作(TIA)的疗效及不良反应。方法将92例短暂性脑缺血发作患者随机分为巴曲酶、低分子肝素、小剂量阿司匹林联合治疗组及应用常规治疗的对照组。观察两组发作终止的时间、不良反应、治疗前后纤维蛋白原变化及出、凝血时间的变化。结果联合治疗组可迅速控制TIA发作,与对照组相比差异有统计学意义(P〈0.05),两组均无严重不良反应。两组均有部分患者发展为脑梗死。结论两种治疗方法均可控制一部分TIA发作,联合治疗组疗效较佳,联合治疗方法亦安全。
作者 张肖师
出处 《中国实用医刊》 2012年第3期96-97,共2页 Chinese Journal of Practical Medicine
  • 相关文献

参考文献4

二级参考文献15

  • 1Desmond DW,Moroney JT,Lynch T,et al. The natural history of CADASIL: A pooled analysis of previously published cases [J]. Stroke, 1999,30:1230-1233.
  • 2Sabbadini G,Francia A,Calandriello L,et al. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Clinical, neuroimaging, pathological and genetic st udy of a large Italian family [J ]. Brain, 1995,118:207-2
  • 3Chabriat H,Mrissa R,Levy C,et al. Brain stem MRI signal abnormalities in CADASIL[J]. Stroke, 1999,30: 457-459.
  • 4Schon F,Martin RJ,Prevett M,et al. ''CADASIL coma'':an underdiagnosed acute encephalopathy[J]. J Neurol Neurosurg Psychiatry, 2003,74: 249-252.
  • 5Uchino M,Hirano T,Uyama E,et al. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) and CADASIL-like disorders in Japan[J].Ann N Y Acad Sci,2002,977:273-278.
  • 6Manabe Y, Murakami T, Iwatsuki K,et al. Nocturnal blood pressure dip in CADASIL[J]. Journal of the Neurological Sciences,2001,193:13 16.
  • 7Engelter ST, Rueegg S, Kirsch EC, et al. CADASIL mimicking primary angiitis of the central nervous system[J]. Arch Neurol,2002,59:1480-1483.
  • 8Mellies JK,Baumer T,Muller JA,et al. SPECT study of a German CADASIL family: a phenotype with migraine and progressive dementia only[J]. Neurology,1998,50:1715-1721.
  • 9Markus HS,Martin RJ,Simpson MA,et al. Diagnostic strategies in CADASIL[J]. Neurology,2002,59:l134-1138.
  • 10de Freitas GR,Miklossy J,Christen-Zach S,et al. A CADASIL case with normal skin biopsy and without mutations in exons 3and 4 of the Notch3 gene[J ]. J Neurol Sci, 2001,193: 43-47.

共引文献35

同被引文献18

引证文献5

二级引证文献44

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部