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间断小量多次微囊化胰岛腹腔移植的实验研究 被引量:2

间断小量多次微囊化胰岛腹腔移植的实验研究
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摘要 微囊化胰岛移植虽已证明是一种治疗IDDM的方法,并用于临床实验,但结果不能令人满意。报道表明,移植使IDDM患者转化为非胰岛素依赖的比率很低,大部分只是减少胰岛素的用量。原因是多方面的。
出处 《世界华人消化杂志》 CAS 2000年第2期228-230,共3页 World Chinese Journal of Digestology
基金 国家教委博士点基金 No.9501009
关键词 胰岛移植 糖尿病 治疗 islets transplantation diabetic mellitus/ therapy
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参考文献5

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同被引文献18

  • 1Bonner-Weir S.Stem cells diabetes:What has been achieved.Horm Res,2003,60:10-12.
  • 2Morini S,Braun M,Onori P,et al.Morphological changes of isolated rat pancreatic islets:a structural,ultrastructural and morphometric study.J Anat,2006,209:381-392.
  • 3Bouwens L.Islet morphogenesis and stem cell markers.Cell Biochem Biophys,2004,40:81-88.
  • 4Rovira M,Scott SG,Liss AS,et al.Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas.Proc Natl Acad Sci USA,2010,107:75-80.
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  • 6Hori Y.Insulin-producing cells derived from stem/progenitor cells:therapeutic implications for diabetes mellitus.Hori Y.Med Mol Morphol,2009,42:195-200.
  • 7Boaan-Sobkowska J,Zabel M,Wozniak W,et al.Polyhormonal aspect of the endocrine cells of the human fetal pancreas.Histochem Cell Biol,1999,112:147-153.
  • 8Hunziker E,Stein M.Nestin-expressing cells in the pancreatic istets of Langerhans.Biochem Biophys Res Conmun,2000,271:116-119.
  • 9Gaghardino JJ,Del Zotto H,Massay L,et al.Pancreatic duodenal homebox-1 and islet neogenseis-associated protein:possible combined marker of activa-teable perxreatic cell precursors.J Endocrinol,2003,177:249-259.
  • 10Huang Y,Kucia M,Hussain LR,et,al.Bone marrow transplantation temporarily improves pancreatic function in streptozotocin-induced diabetes:potential involvement of very small embryonic-like cells.Transplantation,2010,89:677-685.

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