肌钙蛋白Ⅰ定量与心肌酶谱联合检测在小儿病毒性心肌炎临床诊治中的价值

Troponin Ⅰ quantitative and myocardial enzyme joint test in pediatric viral myocarditis clinical diagnosis in the treatment of value

目的探讨肌钙蛋白Ⅰ(cTnI)定量与心肌酶谱联合检测在小儿病毒性心肌炎(VMC)临床诊治中的价值。方法测定47例VMC患儿和53例对照组的血清cTnI、肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)、乳酸脱氢酶(LDH)结果,并比较结果,绘制cTnI、CK、CK-MB、LDH受试者工作曲线(ROC曲线)。结果 VMC组入院时与对照组cTnI、CK、CK-MB、LDH结果差异有统计学意义(P<0.01);治疗2周后cTnI结果与对照组比较,差异有统计学意义(P<0.01);CK、CK-MB、LDH结果与对照组比较,差异无统计学意义(P>0.05)。结论 cTnI定量与心肌酶谱联合检测在小儿VMC诊断中提高了准确性,cTnI在治疗效果监测中起了更好的作用,值得临床常规开展。

Objective To explore Tropoin I quantitative and myocardial enzyme joint test in pediatric viral myocarditis clinical diagnosis in the treatment of value.Methods erum cTnI,CK,CK-MB and LDH of 47 pediatric patients viral myocarditis（VMC）children and 53 patients with healthy controls s were tested.Results were compared and cTnI,CK,CK-MB,LDH receiver operating curves（ROC curve）were drew.Results cTnI,CK,CK-MB,LDH results were significantly different between VMC group and control group（P0.01）.CTnI results after 2 weeks of treatment were significantly different compared with the control group（P0.01）.CK,CK-MB,LDH results were not significantly different compared with the control group（P0.05）.Conclusion cTnI quantitative and myocardial enzyme joint test in the pediatric VMC diagnosis can greatly improve the accuracy,cTnI monitoring treatment in vmc played a better role,worth to often carry out.