1Attarbaschi A, Mann G, Kenig M, et al. Incidence and relevance ofsecondary chromosome abnormalities in childhood TEL/AML1+acutelymphoblastic leukemia:an inter phase FISH analysis[J]. Leukemia,2004,18(10) :1611- 1616.
2Tiensiwakul P. Cloning and sequencing of ETV6/RUNX1 (TEL/ AML1)variant in acute lymphoblastic leukemia[J]. Cancer Genet Cytogenet, 2004,149 ( 1 ) : 85-88.
4De-Zen L,Orfao A,Cazzaniga G, et al. Quantitative multiparamet ric immumophenotyping in acute lymphoblastic leukemia., correla- tion with specific genotype ETV6/AML1 ALLs indentification [J]. Leukemia, 2000,14:1225-1231.
5Loh ML, Goldwasser MA, Silverman 1.13, et al. Prospective analy- sis of TEL/AMLl-positive patients treated on Dana-Farber Canc- er Institute Consortium Protocol 95-01 [J]. 131ood, 2006,107 ( 11 ) : 4508-4513.
6Peter A, Heiden T, Taube T, et al. Interphase FISH on TEL/ AML1 positive acute lymphoblastic leukemia relapses--analysis of clinical relevance of additional TEL and AML1 copy number chan- ges[J]. Eur J Haematol,2009,83(5) :420-32.
7Chung HY, Kim KH, Jun KR, et al. Prognostic significance of TEL/AML1 rearrangement and its additional genetic changes in Korean childhood precursor B-acute lymphoblastic leukemia[J]. Korean J Lab Med,2010,30(1) :1-8.
8Takahashi Y, Horibe K, Kiyoi H, et al. Prognostic significance of TEL AML1 fusion transcrip t in childhood 13-precurs or acute lymphoblasticleukemia[J]. J Pediatr Hem atol Oncol, 1998, 20 (3) :190-195.
9Papadhimitriou SI,Polychronopoulou S,Tsakiridou AA,et al. P16 Inactivation associated with aggressive clinical course and fataloutcome in TEL/AMLl-positive aecute lymphoblastic leukemia [J]. J Pediatr Hematol Oneol,2005,27(12) :675-677.
10Pui CH, Relling MV, Dowing JR. Acute lymphyoblastie leukemia [J]. N Engl J Med,2004,350:1535-1548.
3Dombret H, Gabert J, Boiron JM, et al. Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia-results of the prospective multieenter LALA-94 trial. Blood, 2002, 100 : 2357-2366.
4Radich JP. Philadelphia chromosome-positive acute lymphoblastic leukemia. Hematol Oncol Clin North Am, 2001,15:21-36.
5Lichty BD, Keating A, Callum J, et al. Expression of p210 and p190 BCR-ABL due to alternative splicing in chronic myelogenous leukaemia. Br J Haematol, 1998, 103 : 711-715.
6Gleissner B, Gokbuget N, Bartram CR, et al. Leading prognostic relevance of the BCR-ABL translocations in adult acute B-lineage lymphoblastic leukemia: a prospective study of the German Muhicenter Trial Group and confirmed polymerase chain reaction analysis. Blood, 2002, 99 : 1536-1543.
7Cimino G, Pane F, Ella L,et al. The role of BCR/ABL isoforms in the presentation and outcome of patients with Philadelphiapositive acute lymphoblastic leukemia: a seven-year update of the GIMEMA 0496 trial. Hacmatologica, 2006, 91:377-380.
8Secker-Walker LM, Craig JM. Prognostic implications of breakpoint and lineage heterogeneity in Philadelphia-positive acute lymphoblastic leukemia: a review. Leukemia, 1993,7:147-151.
9Chowdhury T, Brady HJ. Insights from clinical studies into the role of the MLL gene in infant and childhood leukemia. Blood Cells Mol Dis ,2008 ;40 : 192 - 199.
10Saarinen-pihkala UM, Gustafsson G, Carlsen N, et al. Outcome of children with high-risk acute lumphoblastic leukemia (HR-ALL) : nordic results on an intensive regimen with restricted central nervous system irradiation, Pediatr. Blood Cancer,2004 ;42:8 - 23.
5Swerdlow S H,Campo E,Harris N L. World Health Organization classification of tumours of haematopoietic and lymphoid tissues[M].Lyon,France:IARC,2008.
6张之南;沈悌.血液病诊断及疗效标准[M]北京:科学出版社,2007219-227.
7Mr6zek K,Harper D P,Aplan P D. Cytogeneties and molecular genetics of acute lymphoblastic leukemia[J].{H}Hematology Oncology Clinics of North America,2009,(5):991-1010.
8Harrison C J,Moorman A V,Barber K E. Interphase molecular cytogenetic screening for chromosomal abnormalities of prognostic significance in childhood acute lymphoblastic leukaemia:a UK Cancer Cytogenetics Group Study[J].{H}British Journal of Haematology,2005,(4):520-530.
9Moorman A V,Richards S M,Robinson H M. Prognosis of children with acute lymphoblastic leukemia (ALL)and intrachromosomal amplification of chromosome 21 (iAMP21)[J].{H}Blood,2007,(6):2327-2330.
10Pui CH, Evans WE. A 50-year journey to cure childhood acute lymphoblastic leukemia[J]. Semin Hematol, 2013, 50(3): 185- 196.
