化学髓核溶解术治疗腰椎间盘突出症

Treatment of Sequestered Lumbar Disk Herniation with Chemonucleolysis

目的】探讨化学髓核溶解术的一种新的穿刺方法,用于治疗破裂型腰椎间盘突出症。【方法】采用经背后入路直接穿刺椎间盘脱出部位,用600单位的胶原酶溶解脱出的椎间盘组织治疗破裂脱出型腰椎间盘突出症。本组治疗43例临床确诊为破裂脱出型腰椎间盘突出症,并随访半年至2年。【结果】采用本穿刺方法治疗43例腰椎间盘脱出患者,治愈27例,治愈率为63%,有效11例,有效率为88%,无椎间盘变窄和退行性变等并发症出现。【结论】经背后入路直接穿刺脱出的椎间盘组织行胶原酶溶解术是一种操作简单、安全、有效的新方法。

Objective To study a new method of puncture for the treatment of sequestered lumbar disk herniation with chemonucleolysis. Methods Forty three patients with clinically confirmed sequestered lumbar disk herniation underwent the new interventional procedure, which implied the direct via back puncture and a subsequent injection of 600 units of collagenase into the herniated lumbar disk tissue. All the patients were followed up for from half a year to 2 years. Results Of the forty three patients receiving this remedy, 27 were cured(63%) and 11 were regarded as being effective. The total effective rate was 88%. No narrowing of intervertebral space or degeneration of intervertebral disk was noted. Conclusion Via back routepuncture chemonucleolysis is a simple, safe and effective method for the treatment of sequestered lumbar disk herniation with far less complication.